UNILATERAL FACIAL AND LIMB OEDEMA SECONDARY TO FLUOXETINE IN A PATIENT WITH HAEMORRHAGIC STROKE

Received 2021-01-29; Accepted 2021-09-23; Published 2021-11-18

Authors

  • Li-Shun Chua Department of Rehabilitation Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur.
  • Kumaran Ramakrishnan Department of Rehabilitation Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur.
  • Mazlina Mazlan Department of Rehabilitation Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur.

DOI:

https://doi.org/10.22452/jummec.vol25no1.12

Keywords:

Fluoxetine, Motor recovery, Peripheral oedema, stroke, SSRI

Abstract

Fluoxetine is a common selective serotonin reuptake inhibitor (SSRI) used as a pharmacological neuromodulationagent for post-stroke motor recovery and treatment for post-stroke mood disorder. Although some SSRIs are known to cause bilateral symmetrical peripheral oedema, to datethere are no reported cases of oedemacaused by fluoxetine or reported cases of a unilateral peripheral oedema. We report a case of fluoxetine-induced unilateral facial and limb oedema in a patient with haemorrhagic stroke. The peripheral oedema was noted on the hemiparetic side within 48 hours after theinitiation of fluoxetine.The medication was then tapered off over two weeks, which resulted in gradual resolution of the oedema.

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Published

2022-01-20

Issue

Section

Research article