A RARE CASE OF ACUTE MOTOR AXONAL NEUROPATHY IN A ONE-YEAR-OLD MALE CHILD

Received 2024-04-15; Accepted 2024-09-23; Published 2025-02-03

Authors

  • Brinal Shailendrakumar Solanki Department of Pharmacy Practice, Parul Institute of Pharmacy, Parul University, Waghodia, Vadodara-391760, Gujarat, India.
  • Baishakhee Sastiprasada Bishoyi Department of Pharmacy Practice, Parul Institute of Pharmacy, Parul University, Waghodia, Vadodara-391760, Gujarat, India.
  • Jignesh Laxmanbhai Patel Clinical Research Department, Parul University, Waghodia, Vadodara-391760, Gujarat, India.

DOI:

https://doi.org/10.22452/jummec.vol28no1.21

Keywords:

Acute Motor Axonal Neuropathy, Guillain Barre’s Syndrome, Intravenous immunoglobulin

Abstract

Acute Motor Axonal Neuropathy (AMAN), a major subtype of Guillain Barre’s Syndrome (GBS), is a rare non-inflammatory disease where the axons of motor neurons are selectively targeted by the immune system. This report describes the case of a one-year-old male suffering from this rare condition. The patient presented with complaints of bilateral lower and upper limb weakness, accompanied by fever. Clinical and electromyographic investigations confirmed the diagnosis as AMAN. Treatment included intravenous immunoglobulin (IVIg), antibiotics, multivitamins, zinc, and physiotherapy, which led to significant improvement in the patient’s condition. Early diagnosis, along with prompt initiation of IVIg and physiotherapy, may greatly enhance recovery from GBS-AMAN in pediatric patients.

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Author Biographies

Brinal Shailendrakumar Solanki, Department of Pharmacy Practice, Parul Institute of Pharmacy, Parul University, Waghodia, Vadodara-391760, Gujarat, India.

Dr Brinal Solanki is working at Parul Sevashram Hospital, Parul Institute of Pharmacy, Parul University, Waghodia, Vadodara-391760, Gujarat, India. Her area of expertise includes immunology, oncology and writing case reports on various medical cases.

Baishakhee Sastiprasada Bishoyi, Department of Pharmacy Practice, Parul Institute of Pharmacy, Parul University, Waghodia, Vadodara-391760, Gujarat, India.

Dr Baishakhee Bishoyi is working at Department of Pharmacy Practice, Parul Institute of Pharmacy, Parul University, Waghodia, Vadodara-391760, Gujarat, India. Her areas of expertise includes clinical pharmacology, clinical research and writing manuscript and case reports.

Jignesh Laxmanbhai Patel, Clinical Research Department, Parul University, Waghodia, Vadodara-391760, Gujarat, India.

Dr. Jignesh Patel is Professor and Head: Clnical Research at Parul Sevashram Hospital, Parul University, Waghodia, Vadodara-391760, Gujarat, India. He is a medical and clinical research scientist with more than 20 years of experience in pharmaceutical and medical device clinical research. His areas of expertise include translational research and first-in-human clinical trials, SAD-MAD studies and various clinical pharmacology studies of medical devices, drugs and modified release formulations, NDDS, biologics, biosimilars and vaccines. He had published >40 scientific papers in various scientific journals. He has received many national and international awards for his research work and scientific publications. During his early career, he has worked as CRC at various hospital sites and has handled clinical trials of global pharma industries including Sanofi, GSK, Pfizer, BMS, Boehringer Ingelheim, J & J, Medtronic etc. for various CROs like Quintiles, Covance, ICON, PPD etc. He has also worked as a project manager for global clinical trial and have handled EU and UK sites. He has directly led the clinical development of more than 10 NCEs-based INDs, more than 14 NDDS, 37 medical devices, 3 Biosimilars, 2 Biologics, 2 vaccines & more than 140 generic products for USFDA, EMA, MHRA, ANVISA, CDSCO, Malaysia and many other regulated markets.

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Published

2025-02-03

Issue

Vol. 28 No. 1 (2025)

Section

Research article

License

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